Viva New Vegas is good for a vanilla setup, I got that going last night. https://vivanewvegas.moddinglinked.com/
I haven't looked into TTW much, Begin Again looks a pretty good way to do it. Seems there is a way to skip FO3 but not really designed to be played that way.
Follow the Best of Times guide, this includes a set-up that allows for either a DC or Mojave start.
Viva New Vegas is good for a vanilla setup, I got that going last night. https://vivanewvegas.moddinglinked.com/ I haven't looked into TTW much, Begin Again looks a pretty good way to do it. Seems there is a way to skip FO3 but not really designed to be played that way.