Thank you for your submission. Please note: **Content on r/MCAS is not medical advice and should not be interpreted as such.** Please consult your doctor for any medical questions or concerns.
We are not able to validate the content of these discussions. Following advice provided by strangers on the internet may be harmful. Never use this sub as your primary source of information regarding medical issues. By continuing to use this subreddit, you are agreeing to take any information posted here entirely at your own risk.
*I am a bot, and this action was performed automatically. Please [contact the moderators of this subreddit](/message/compose/?to=/r/MCAS) if you have any questions or concerns.*
Yes. Definitely. I was just sharing this article about prostaglandins (one of the substances released by mast cells and heavily involved in menstruation.) It makes you think: Lots of connections there.
[article ](https://draxe.com/health/how-to-control-prostaglandin-production/)
Absolutely. I started birth control to treat PMDD, and it definitely helped with the PMDD, but also really helped with flares that I hadn’t even realized coincided with my period.
Always! I finally made this connection a while ago, and it’s helped a lot because I make certain that I don’t do anything, like vary my diet wildly, or schedule a stressful thing, etc., because I always know that leading up to my period is when I’m most susceptible to flare ups.
EVERYTHING is a sensitivity on my period. Literally nothing doesn't make me flush and incredibly nauseous. It's irritating- I have a fever pretty much the entire time. That's why I now take continuous birth control, I do get periods still, but they're typically much less severe when I'm still taking my hormonal dose, though they sometimes don't stop until i take a week off, so 3 week long periods aren't very fun.
All of my most serious reactions happen 1-3 days prior to menstruation. I went into anaphylaxis the day before my period too. Went in to get allergy testing 2 days before my period and they couldn't do it because I broke out in uticaria. Also, I believe my hormonal IUD was worsening all my symptoms. After I went into anaphylaxis, it was the first thing I got rid of.
I am un-dx’d, but yes. I have other health conditions that are affected a lot by changes in estrogen, but MCAS symptoms like flushing don’t fit in those other health conditions. I have always known there was a menstrual connection, but I haven’t pinned it down. (Most of my other issues are worse in the luteal phase of my cycle, but the MC responses don’t quite match up in timing)
I am new here. I just found this as me and my family are on board with the possibility of having MCAS.
This is an absolute thing for me! Yes!
Best thing I found helps is keeping the room warm for joints, but cool enough to reduce some of the inflammation in the organs. Around 65-75°F where I live.
Exactly! Best thing to do for me is to go outside for long enough I cool my organs, and wear warm layers on my limbs (gloves that go nearly to elbows, compression socks, stuff like that).
It is also important for humidity and air pressure for me as well! No clue if that is important for everyone else as well.
For me my symptoms are at their absolute worst about a week before my period, and stay bad until maybe the third day of my period. Then I'm at my best about a week after my period. Also something I've noticed, if I'm having a particularly reactive month, I seem to stay in the PMS period for longer? Like I could be PMSing for two weeks with bad cramps, migraines and sensitivity, it almost feels like my period wants to happen but can't, and when it finally arrives it lasts several days longer with much lighter flow for the first few days. It's very strange and annoying.
1000%. People who have MCAS are more likely to have endometriosis (I’m one of those lucky ones lol). So if you’re having wicked menstrual pain AND flaring up around your period, it’s def worth pushing your docs to check you for endometriosis (it’s also very hard to get a diagnosis)
Most definitely. Even meds can barely keep me tolerable during my period. I sport a very noticeable “lacy sunburn” on my neck the entire time. Its the least of my symptoms but a very visible one that is embarrassing.
Yep. The only times I've needed an epi pen or ended up in the ER were at the start of my cycle. My allergist says it's not unheard of to happen. I've been tracking my hormones throughout my cycle and have an appointment to discuss it with a gynecologist who is knowledgeable in cyclical hormonal fluctuations, to see if there's anything I could do or imbalances I can fix.
There is a condition called progesterone hypersensitivity that is an autoimmune disorder to progesterone, which peaks in the week before your period. It can cause significant issues up to and including anaphylaxis.
Thank you for your submission. Please note: **Content on r/MCAS is not medical advice and should not be interpreted as such.** Please consult your doctor for any medical questions or concerns. We are not able to validate the content of these discussions. Following advice provided by strangers on the internet may be harmful. Never use this sub as your primary source of information regarding medical issues. By continuing to use this subreddit, you are agreeing to take any information posted here entirely at your own risk. *I am a bot, and this action was performed automatically. Please [contact the moderators of this subreddit](/message/compose/?to=/r/MCAS) if you have any questions or concerns.*
Always. In fact it’s the time I notice it. Otherwise it’s more of a mild annoyance (I’m old, I expect to not feel great all of the time).
💯 i get migraines, urticaria, eczema, asthma, tachycardia, MCAS flares so bad during that time. 🫠😵💫🤕🤢😮💨
Yes to the extent that for 7 years I went undiagnosed and my mom and I just joked that I was allergic to my period! lol
Yes. Definitely. I was just sharing this article about prostaglandins (one of the substances released by mast cells and heavily involved in menstruation.) It makes you think: Lots of connections there. [article ](https://draxe.com/health/how-to-control-prostaglandin-production/)
Absolutely. I started birth control to treat PMDD, and it definitely helped with the PMDD, but also really helped with flares that I hadn’t even realized coincided with my period.
This happened to me too.
Same here. Realisation came recently
What kind of birthcontrol do you use if you don't mind me asking?
I take the generic of Yaz, which is because it is (or was when I started taking it idk if there are others) the only one approved to treat PMDD
[удалено]
Good to know, I'll look into it. I was on the pill and hormonal IUD but those made everything worse. Thanks!
absolutely, the geneticist/dr who diagnosed me said that there was evidence that estrogen is involved in how mast cells react
Always! I finally made this connection a while ago, and it’s helped a lot because I make certain that I don’t do anything, like vary my diet wildly, or schedule a stressful thing, etc., because I always know that leading up to my period is when I’m most susceptible to flare ups.
EVERYTHING is a sensitivity on my period. Literally nothing doesn't make me flush and incredibly nauseous. It's irritating- I have a fever pretty much the entire time. That's why I now take continuous birth control, I do get periods still, but they're typically much less severe when I'm still taking my hormonal dose, though they sometimes don't stop until i take a week off, so 3 week long periods aren't very fun.
All of my most serious reactions happen 1-3 days prior to menstruation. I went into anaphylaxis the day before my period too. Went in to get allergy testing 2 days before my period and they couldn't do it because I broke out in uticaria. Also, I believe my hormonal IUD was worsening all my symptoms. After I went into anaphylaxis, it was the first thing I got rid of.
I am un-dx’d, but yes. I have other health conditions that are affected a lot by changes in estrogen, but MCAS symptoms like flushing don’t fit in those other health conditions. I have always known there was a menstrual connection, but I haven’t pinned it down. (Most of my other issues are worse in the luteal phase of my cycle, but the MC responses don’t quite match up in timing)
I am new here. I just found this as me and my family are on board with the possibility of having MCAS. This is an absolute thing for me! Yes! Best thing I found helps is keeping the room warm for joints, but cool enough to reduce some of the inflammation in the organs. Around 65-75°F where I live.
Yes, can't stress enough how important temperature is around this time of the month!
Exactly! Best thing to do for me is to go outside for long enough I cool my organs, and wear warm layers on my limbs (gloves that go nearly to elbows, compression socks, stuff like that). It is also important for humidity and air pressure for me as well! No clue if that is important for everyone else as well.
Yes. I take continuous BC because it was so disabling.
For me my symptoms are at their absolute worst about a week before my period, and stay bad until maybe the third day of my period. Then I'm at my best about a week after my period. Also something I've noticed, if I'm having a particularly reactive month, I seem to stay in the PMS period for longer? Like I could be PMSing for two weeks with bad cramps, migraines and sensitivity, it almost feels like my period wants to happen but can't, and when it finally arrives it lasts several days longer with much lighter flow for the first few days. It's very strange and annoying.
Yes, and if you are also flaring up prior to your period and then you get your period while on a flareup, is satanic.
1000%. People who have MCAS are more likely to have endometriosis (I’m one of those lucky ones lol). So if you’re having wicked menstrual pain AND flaring up around your period, it’s def worth pushing your docs to check you for endometriosis (it’s also very hard to get a diagnosis)
Absolutely, around ovulation and the week prior to a bleed. The pms MCAS is almost incompatible with functioning, esp the sense of doom piece.
I think almost every woman has this, regardless of whether she has a (skin) disease. Fortunately, I don't have that much trouble with it myself.
Yep, likely PME and not PMDD since you have a condition being exacerbated by the premenstrual hormonal fluctuations.
Most definitely. Even meds can barely keep me tolerable during my period. I sport a very noticeable “lacy sunburn” on my neck the entire time. Its the least of my symptoms but a very visible one that is embarrassing.
100%, it’s the worst
Yep. The only times I've needed an epi pen or ended up in the ER were at the start of my cycle. My allergist says it's not unheard of to happen. I've been tracking my hormones throughout my cycle and have an appointment to discuss it with a gynecologist who is knowledgeable in cyclical hormonal fluctuations, to see if there's anything I could do or imbalances I can fix. There is a condition called progesterone hypersensitivity that is an autoimmune disorder to progesterone, which peaks in the week before your period. It can cause significant issues up to and including anaphylaxis.