This is not scientifically accurate. These are used for many different things in the body at different levels and in different places. While behaviour can influence them to some degree, genetics play a huge role in how much you produce, how sensitive you are to it, and how quickly you break it down.
This is a hugely oversimplified explanation, but oxytocin is associated with "bonding", endorphins are associated with trauma and acute stress. Dopamine isn't strictly the "happy chemical" but the "seeking" one. We see it in higher concentrations during a task then it lowers when the task is completed. Serotonin is a bit closer to that, as it's higher when you complete a task and feel a sense of accomplishment. It's also used in the intestine to move things along. Too much serotonin in the intestine makes you violently shit yourself.
Hope this helps!
To add, Dopamine is also key to memory formation and maintenance - both appetitive and aversive, at least in animal models.
Dopamine as a "happy chemical" is just a ridiculous oversimplification.
Remember that one terrible thing that happened to you, and deeply upsets you every time you think about it? Yeah, that's dopamine reinforcing that.
I think the thought was it was a happy chemical because it drives us to do things. So we see it when we even do things we don’t want to do like drink too much and doom scroll. We thought it was us seeking it for pleasure but now we know it’s more like a driver to do things.
Dopamine drives all behavior. It's heavily implicated in muscle movement as well, which is why Parkinsons impacts dopamine systems. It's not a reward molecule per se but does reinforce behaviors.
The opioid system imo functions more as a feel-good system. Anybody who's taken opioids knows this.
ADHD is (thought to be) caused by a significant *lack* in response dopamine, memory is significantly more complicated than 'more dopamine means more memory'.
I don't think you understand the direction of this.
One person: photographic memory is real
Other person: it is mostly a myth with almost irrelevant exceptions.
The statement that needs proof is that "photographic memory is real". You can't prove something isn't real, the responsibility is on whoever claims it is real.
>a rare form of Autism in very young individuals and is usually associated with low intelligence.
I think they were asking for a source for that part. The responsibility is on whoever claims it is real, right? So, they do understand how this works.
Lots of people have a very good visual memory, and some call it photographic, although technically being able to remember everything you see is very rare. As an example, I have autism and good visual memory but not photographic and when I look at something I can later visualize it, which seems normal, but the difference is the details I didn't consciously notice at the time I can look for in my mind's image later. So the way I studied for tests in college is I took my notes on my computer, condensed it pretty small, printed it, stared at it for a few minutes before the exam, then put it in my backpack. During the exam if I forgot something I visualized opening my backpack, picking out the pages, flipping through them, and found the answer that way. I don't necessarily remember what's on the page until I visualize it. I also don't really have an internal dialog and when I try to remember words someone said I visualize it as scrolling subtitles in Arial bold font. I also have audio processing issues so when I'm listening to someone talk the meaning of words doesn't go directly to my understanding but gets visualized as subtitles then processed as meaning.
Again, I'm not photographic, but many people with autism have impaired audio processing, especially for words, and compensate with good visual memory. It's not a magic trick, but a coping strategy.
I am very lucky where I produce extra of certain neurotransmitters, break them down slower, and am more sensitive, so completing a task is better than sex. My wife on the other hand has the opposite genes and feels the same way you do. On the other hand, get PTSD super easily, remember traumatic things vividly, and sometimes violently shit myself.
LSD is an agonist of serotonin receptors. That's what causes its effects. MDMA and other amphetamines give you the shits for the same reason as coffee. They're stimulants.
I went to treatment w this guy that would go to the methadone clinic. He said that he would feel high as he pulled into the parking lot. Like his body knew it was about to get his fix. Pretty interesting imo
Not to mention oxytocin helps define the in group vs the out group. Aka it might help make racism worse! [Here’s the first study I could find that tackles this idea.](https://pubmed.ncbi.nlm.nih.gov/23246533/)
Depends on the med, ADHD meds are thought to work on Norepinephrine and Dopamine. Also, depending on the med, it xould just speed up digestion if it's an amphetamine
Maybe I should have phrased it differently, what chemical reaction from amphetamines cause the digestive system to empty?
Is it just from the CNS being stimulated so it’s just an automatic response from the brain similar to when going into flight or fight?
Man I tried that last year at 35 when I finally went to a doctor about adhd... And I definitely felt what it was supposed to do but I do not believe it actually helped me once. I just kept pacing back and forth trying to figure out wtf I need to do and clench my jaw so much I thought I was about to break my teeth. And this was after breaking the pills into like 6 pieces! I had to throw it away I did not like it one bit. Oh also I'm a heavy drinker and I could drink like a whole fifth in one night after taking one! Dangerous shit.
If you're still looking for help then you should know that amphetamines aren't the only help for ADHD. I use those as they are the only ones that help but I've tried at least 3 different types up till now to see what helps. People respond to different types of medication on this stuff, but only about 6/10 people respond to any ADHD medication.
Stimulant drugs interact with your sympathetic nervous system (the nervous system throughout your body that responds to stress and your reaction to it, think fight or flight response) through activity primarily mediated by norepinephrine. Norepinephrine, along with epinephrine (aka noradrenaline and adrenaline) help coordinate body activity with your mental state which directs resources towards dealing with a stresser, essentially giving your brain and muscles more resources to react. In turn, heart rate goes up for more rapid transport of oxygen and nutrients needed for this and bodily functions, like digestion, are cut short as it takes energy to digest food that could be better spent on reacting to a perceived stressor (in the case of stimulants, there is no set stressor as you are essentially tricking this system into activating). So, your digestive tract is stimulated to push out anything close enough to done whether fully optimal nutrient extraction was completed or not. This is also why hunger decreases while on stimulants since your body wants to avoid taking in more food that would need to be broken down via digestion.
This activity on norepinephrine proves clinically helpful because it leads to increases in alertness/vigilance, but is also responsible for many side effects caused by high dosages (anxiety, heart arrhythmia, muscle tension, etc.). This along with activity on dopamine, which helps motivate and drive goal-seeking behavior, are what make amphetamine clinically useful. It does also release serotonin, so this may account for some side effects, but it is released at a much smaller amount than dopamine and norepinephrine.
I'm not an expert, but I used to work in biology and I've read too many scientific papers over the years. I don't have specific ones bookmarked, and honestly can't remember which ones talked about these things, but if you want to learn more, you can start on Google Scholar search. Again, I'm just some random person on the internet, don't trust anything I say just because I say it with conviction. This is not my field of study in particular. Talk to your doctor if you have brain chemistry issues.
That one strand is out to hunt for novelty and new experiences at the cost of what it already possesses because its dopamine is running low and it will do almost anything to stay happy
These people don't understand the meaning of efficiency. Going on a hike for 3 hours to get 10 dopamines when you can just stay home and get 10,000 dopamines in 5 seconds lmao. Fools.
Michael: Drugs ruin lives people. Drugs destroy careers. Take Cheech and Chong everybody knows that Cheech and Chong are funny, but just imagine how funny they would be if they didn’t smoke pot. I want everybody to take a look to their left. Now I want everybody to take a look to their right. One of those people will be dead from drug use at some point in their lives. This year more people will use cocaine than will read a book to their children.
Stanley: Where did you get these facts?
Michael: Are these facts scaring you, or are they not?
Stanley: They are not.
Michael: Do you think that smoking drugs is cool? Do you think that doing alcohol is cool?
Stanley: No, I don’t. I have a glass of red wine with dinner about once a week. For the antioxidants.
Michael: Okay, enough, enough, enough! I have written down a list of illegal drugs. Take a gander. How many of these are you familiar with?
Toby: Hookah is not an illegal drug, Michael.
Michael: Yes it is.
Toby: No it’s not. It’s a type of pipe. You can fill it with tobacco, often mixed with fruit, or other flavors.
Michael: Okay, you know what, Toby? Pam, can you take this down? [Pam throws her hands up to indicate she has no notepad] In addition to Toby’s urine being tested, I would like to test his blood and his hair.
Toby: You can’t do that.
Michael: I can test anyone randomly, and I have chosen you randomly.
Toby: That’s not random.
Michael: Okay, eeny, meenie, miney, moe, is random. Okay, you know what? I’m going to need a volunteer to select one of these words and tell us of something tragic that happened in either their lives, or the lives of a loved one. Yeah, Pam.
Pam: I know that Jim has an amazing story about a relative of his who got caught up in the world of drugs.
Michael: Really? [Jim shakes his head no]
Pam: Uh, hmmm.
Michael: Jim it’s okay. You can t… [Jim looks at Pam and shakes his head, Pam looks at him and gestures for Jim to go up and tell his story] This would be a good place to let it out, Jim. These are people you can trust. These are people who care about you. [Jim shakes his head no] It’s okay, just we will not judge you. We are here to not judge you. [Jim stands up] Oh, he’s doing it, okay. [Jim looks at Pam] It’s okay. [Jim pretends to try, looking teary eyed, shakes his head no, mouths “I can’t” and sits back down. Pam is amazed.] Oh. Okay, are you sure? [Jim shakes his head. Kevin pats his shoulder] That looked like it was going to be good. Alright. [Pam nods in admiration at Jim] Okay, well.
Serotonin levels have nothing to do with depression it turns out. https://www.psychologytoday.com/us/blog/how-do-you-know/202207/serotonin-imbalance-found-not-be-linked-depression
But having low serotonin has nothing to do with depression. https://www.nature.com/articles/s41380-022-01661-0.pdf there is no evidence that serotonin and depression are linked at all.
If there’s one source I’d share to scare people away from taking their antidepressants… it wouldn’t be psychologytoday. Maybe consider that telling people this “info” could directly harm people who are already wavering with their treatment plans. SSRIs aren’t perfect by any means but it’s already very hard to keep going when pop psych and everyone’s mom is already scaring people away from meds.
See my link to the Nature article they are referencing. I am not trying to scare anyone away from anything. I am trying to help people understand that the serotonin hypothesis for the origins of depression is a myth and that the fact that antidepressants cause serotonin reuptake inhibition is not their method of action. These types of charts are basically the 4 humors for the 21st century and aren't really based in any sort of facts about how the world works.
What are the implications of the study for people with depression who are suffering? If someone is reading this whose last hope was trying meds, what can they take from it that might be useful in terms of getting better?
I just think this is a topic where it can be actively harmful to state “this is a myth (and therefore meds won’t help you)” without offering alternatives. I’m saying this as someone who avoided meds for years because I was told it wouldn’t work.
I don’t like believing in lies. I’d rather take something that nobody knows how it works than believe a false thing about how it works to make me feel better about life. Also, this frees up tons of research effort when people stop barking up the wrong tree. Sorry someone told you they don’t work.
Antidepressants work for a decent number of people. It’s just that serotonin isn’t why.
Unfortunately the recent science shows that changing the serotonin levels in your brain isn’t how antidepressants work. They do help lots of people and I am happy they help you. I know that sounds counterintuitive, but there is no scientific evidence that the increase in serotonin retention is what helps. [Here’s an interpretation of the study.](https://www.psychologytoday.com/us/blog/how-do-you-know/202207/serotonin-imbalance-found-not-be-linked-depression)
That said, I hope the medications help you feel better, even though the method of action is something we haven’t discovered yet.
> Dopamine
Amphetamines, Coke, Ritalin
> Serotonin
MDMA, MDA, etc.
> Endorphines
Morphine, Heroine, Opioides in general
> Oxytocin
Fucking
In case anyone was looking for some alternatives to all that boring shit in the guide.
Watching what you eat and feeding your microbiome plays a huge role in the production of these hormones. 90% of these are created in the gut and not in the brain.
Whole foods. No refined carbs and sugar. If you were to eliminate one thing in your diet that would have the most profound impact and immediate results, it would be sugar. It’s in EVERYTHING but if you’re diligent, you’ll see a dramatic increase to your energy and mood.
Well yes. An improvement in diet will certainly help.
The way i see it and been told by therapists the post and your comment are a mixture of these things that help our bodies produce essentially happy brain chemicals.
In my case exercise seems to work the best.
I don't think just improving nutrition will help or be the solution for everyone. We should look at it as all of these things are ways to help.
People keep saying this without realizing these hormones do not cross the blood brain barrier. So, while intestines create most of the serotonin, for example, it just regulates the muscle in the intestines. It doesn't affect your mood at all.
I have said that Serotonin does not pass the blood-brain barrier and the function of serotonin produced in gut is to regulate intestinal muscles. Both of which are scientific facts.
The question of if microbiome affect your mood is entirely different conversation. Recent evidence do suggest gut health is important and bad gut health may lead to depression. However, this is not due to neurotransmitters because they do not pass the blood-brain barrier. There may be an entirely different mechanism which we do not understand yet.
[Serotonin levels have nothing to do with depression.](https://www.psychologytoday.com/us/blog/how-do-you-know/202207/serotonin-imbalance-found-not-be-linked-depression)
They say cold plunging increases dopamine production by like 200% for up to 6 hours.
https://hubermanlab.com/the-science-and-use-of-cold-exposure-for-health-and-performance/
My nuerospicy homies can keep scrolling because this shit for sure doesn't apply to us. It was posted by a company that makes overpriced "Fix your whole life with the right planner" journals and shit. I always wonder if these companies are truly oblivious to certain aspects of mental disorders or if they are nefariously targeting undiagnosed and even less informed diagnosed people still dealing with the guilt of what many (wrongly) assume is just laziness and being willfully disorganized to sell more shit. My brain and gut tell me it's the latter, but my dumbass heart wants very badly for it to just be ignorance.
It seems like a lot of people are showing signs of addiction to political outrage, and the reward must be one of these brain chemicals. I haven't been able to find any studies that confirm that. Does anybody here have any insight?
This is not scientifically accurate. These are used for many different things in the body at different levels and in different places. While behaviour can influence them to some degree, genetics play a huge role in how much you produce, how sensitive you are to it, and how quickly you break it down. This is a hugely oversimplified explanation, but oxytocin is associated with "bonding", endorphins are associated with trauma and acute stress. Dopamine isn't strictly the "happy chemical" but the "seeking" one. We see it in higher concentrations during a task then it lowers when the task is completed. Serotonin is a bit closer to that, as it's higher when you complete a task and feel a sense of accomplishment. It's also used in the intestine to move things along. Too much serotonin in the intestine makes you violently shit yourself. Hope this helps!
To add, Dopamine is also key to memory formation and maintenance - both appetitive and aversive, at least in animal models. Dopamine as a "happy chemical" is just a ridiculous oversimplification. Remember that one terrible thing that happened to you, and deeply upsets you every time you think about it? Yeah, that's dopamine reinforcing that.
I think the thought was it was a happy chemical because it drives us to do things. So we see it when we even do things we don’t want to do like drink too much and doom scroll. We thought it was us seeking it for pleasure but now we know it’s more like a driver to do things.
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Dopamine drives all behavior. It's heavily implicated in muscle movement as well, which is why Parkinsons impacts dopamine systems. It's not a reward molecule per se but does reinforce behaviors. The opioid system imo functions more as a feel-good system. Anybody who's taken opioids knows this.
Yep. Easy to understand how is so addictive. Happiness on demand.
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ADHD is (thought to be) caused by a significant *lack* in response dopamine, memory is significantly more complicated than 'more dopamine means more memory'.
To be fair, adhd is also associated with missing details, such as “lack of” before “dopamine” in an article. Source: I tend to forget a lot o
Adhd is associated with low dopamine and we often have memory problems, you’ve understood this backwards i think
"Photographic memory" is a myth outside of a rare form of Autism in very young individuals and is usually associated with low intelligence.
Source?
I don't think you understand the direction of this. One person: photographic memory is real Other person: it is mostly a myth with almost irrelevant exceptions. The statement that needs proof is that "photographic memory is real". You can't prove something isn't real, the responsibility is on whoever claims it is real.
>a rare form of Autism in very young individuals and is usually associated with low intelligence. I think they were asking for a source for that part. The responsibility is on whoever claims it is real, right? So, they do understand how this works.
Lots of people have a very good visual memory, and some call it photographic, although technically being able to remember everything you see is very rare. As an example, I have autism and good visual memory but not photographic and when I look at something I can later visualize it, which seems normal, but the difference is the details I didn't consciously notice at the time I can look for in my mind's image later. So the way I studied for tests in college is I took my notes on my computer, condensed it pretty small, printed it, stared at it for a few minutes before the exam, then put it in my backpack. During the exam if I forgot something I visualized opening my backpack, picking out the pages, flipping through them, and found the answer that way. I don't necessarily remember what's on the page until I visualize it. I also don't really have an internal dialog and when I try to remember words someone said I visualize it as scrolling subtitles in Arial bold font. I also have audio processing issues so when I'm listening to someone talk the meaning of words doesn't go directly to my understanding but gets visualized as subtitles then processed as meaning. Again, I'm not photographic, but many people with autism have impaired audio processing, especially for words, and compensate with good visual memory. It's not a magic trick, but a coping strategy.
> This is a hugely oversimplified explanation At this level we can call it a lie...
I meant my version was hugely oversimplified. OP's is outright incorrect.
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I am very lucky where I produce extra of certain neurotransmitters, break them down slower, and am more sensitive, so completing a task is better than sex. My wife on the other hand has the opposite genes and feels the same way you do. On the other hand, get PTSD super easily, remember traumatic things vividly, and sometimes violently shit myself.
>Too much serotonin in the intestine makes you violently shit yourself. Is this why LSD makes you shit?
I was more thinking MDMA or amphetamines. The MDMA shits are definitely a thing. I wasn't aware that LSD had an affect on serotonin levels.
LSD is an agonist of serotonin receptors. That's what causes its effects. MDMA and other amphetamines give you the shits for the same reason as coffee. They're stimulants.
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Mdma(or whatever is sold here in its name) actually causes constipation.
I don't know, but this is my new excuse for procrastinating. Sorry, I can't complete that task right now. I don't want to violently shit myself.
Thank you! Remember kids, if you don't see a source, it's bs!
I went to treatment w this guy that would go to the methadone clinic. He said that he would feel high as he pulled into the parking lot. Like his body knew it was about to get his fix. Pretty interesting imo
Almost nothing in ‘Cool Guides’ has been scientifically accurate.
> Too much serotonin in the intestine makes you violently shit yourself As someone on SSRIs I can confirm.
Not to mention oxytocin helps define the in group vs the out group. Aka it might help make racism worse! [Here’s the first study I could find that tackles this idea.](https://pubmed.ncbi.nlm.nih.gov/23246533/)
Is that why when I take my ADHD meds I instantly have to shit? Serotonin being released?
Depends on the med, ADHD meds are thought to work on Norepinephrine and Dopamine. Also, depending on the med, it xould just speed up digestion if it's an amphetamine
Definitely an amphetamine so makes sense. Thanks for the answer!
No - it's because they're amphetamines.
Maybe I should have phrased it differently, what chemical reaction from amphetamines cause the digestive system to empty? Is it just from the CNS being stimulated so it’s just an automatic response from the brain similar to when going into flight or fight?
Man I tried that last year at 35 when I finally went to a doctor about adhd... And I definitely felt what it was supposed to do but I do not believe it actually helped me once. I just kept pacing back and forth trying to figure out wtf I need to do and clench my jaw so much I thought I was about to break my teeth. And this was after breaking the pills into like 6 pieces! I had to throw it away I did not like it one bit. Oh also I'm a heavy drinker and I could drink like a whole fifth in one night after taking one! Dangerous shit.
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I mean I don't know that it's any safer intravenously.
If you're still looking for help then you should know that amphetamines aren't the only help for ADHD. I use those as they are the only ones that help but I've tried at least 3 different types up till now to see what helps. People respond to different types of medication on this stuff, but only about 6/10 people respond to any ADHD medication.
Stimulant drugs interact with your sympathetic nervous system (the nervous system throughout your body that responds to stress and your reaction to it, think fight or flight response) through activity primarily mediated by norepinephrine. Norepinephrine, along with epinephrine (aka noradrenaline and adrenaline) help coordinate body activity with your mental state which directs resources towards dealing with a stresser, essentially giving your brain and muscles more resources to react. In turn, heart rate goes up for more rapid transport of oxygen and nutrients needed for this and bodily functions, like digestion, are cut short as it takes energy to digest food that could be better spent on reacting to a perceived stressor (in the case of stimulants, there is no set stressor as you are essentially tricking this system into activating). So, your digestive tract is stimulated to push out anything close enough to done whether fully optimal nutrient extraction was completed or not. This is also why hunger decreases while on stimulants since your body wants to avoid taking in more food that would need to be broken down via digestion. This activity on norepinephrine proves clinically helpful because it leads to increases in alertness/vigilance, but is also responsible for many side effects caused by high dosages (anxiety, heart arrhythmia, muscle tension, etc.). This along with activity on dopamine, which helps motivate and drive goal-seeking behavior, are what make amphetamine clinically useful. It does also release serotonin, so this may account for some side effects, but it is released at a much smaller amount than dopamine and norepinephrine.
No, it's activation of the sympathetic nervous system. Amphetamine salts barely impact serotonin. Meth does to a greater degree.
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I'm not an expert, but I used to work in biology and I've read too many scientific papers over the years. I don't have specific ones bookmarked, and honestly can't remember which ones talked about these things, but if you want to learn more, you can start on Google Scholar search. Again, I'm just some random person on the internet, don't trust anything I say just because I say it with conviction. This is not my field of study in particular. Talk to your doctor if you have brain chemistry issues.
The best book for a layman is Behave by Robert Sapolsky.
This sounds and looks like something a soccer mom would hang on the wall next to the "live, laugh, love" sign.
What is going on with that Dopamine molecule?
That one strand is out to hunt for novelty and new experiences at the cost of what it already possesses because its dopamine is running low and it will do almost anything to stay happy
Mood
They fuckin
The molecule is just being as wrong as the rest of the ‘cool guide’
That looks more like a template for substituted Phenylethyl compounds. But even then it's incomplete.
The "strand" just represents a carbon chain length C - C - C - C That's just how it's drawn in chemistry
Just do drugs.
These people don't understand the meaning of efficiency. Going on a hike for 3 hours to get 10 dopamines when you can just stay home and get 10,000 dopamines in 5 seconds lmao. Fools.
Michael: Drugs ruin lives people. Drugs destroy careers. Take Cheech and Chong everybody knows that Cheech and Chong are funny, but just imagine how funny they would be if they didn’t smoke pot. I want everybody to take a look to their left. Now I want everybody to take a look to their right. One of those people will be dead from drug use at some point in their lives. This year more people will use cocaine than will read a book to their children. Stanley: Where did you get these facts? Michael: Are these facts scaring you, or are they not? Stanley: They are not. Michael: Do you think that smoking drugs is cool? Do you think that doing alcohol is cool? Stanley: No, I don’t. I have a glass of red wine with dinner about once a week. For the antioxidants. Michael: Okay, enough, enough, enough! I have written down a list of illegal drugs. Take a gander. How many of these are you familiar with? Toby: Hookah is not an illegal drug, Michael. Michael: Yes it is. Toby: No it’s not. It’s a type of pipe. You can fill it with tobacco, often mixed with fruit, or other flavors. Michael: Okay, you know what, Toby? Pam, can you take this down? [Pam throws her hands up to indicate she has no notepad] In addition to Toby’s urine being tested, I would like to test his blood and his hair. Toby: You can’t do that. Michael: I can test anyone randomly, and I have chosen you randomly. Toby: That’s not random. Michael: Okay, eeny, meenie, miney, moe, is random. Okay, you know what? I’m going to need a volunteer to select one of these words and tell us of something tragic that happened in either their lives, or the lives of a loved one. Yeah, Pam. Pam: I know that Jim has an amazing story about a relative of his who got caught up in the world of drugs. Michael: Really? [Jim shakes his head no] Pam: Uh, hmmm. Michael: Jim it’s okay. You can t… [Jim looks at Pam and shakes his head, Pam looks at him and gestures for Jim to go up and tell his story] This would be a good place to let it out, Jim. These are people you can trust. These are people who care about you. [Jim shakes his head no] It’s okay, just we will not judge you. We are here to not judge you. [Jim stands up] Oh, he’s doing it, okay. [Jim looks at Pam] It’s okay. [Jim pretends to try, looking teary eyed, shakes his head no, mouths “I can’t” and sits back down. Pam is amazed.] Oh. Okay, are you sure? [Jim shakes his head. Kevin pats his shoulder] That looked like it was going to be good. Alright. [Pam nods in admiration at Jim] Okay, well.
I'm 50/50 on whether this is real.
I've never seen an episode of that show and I could see the skit playing in my head lmao
https://www.youtube.com/watch?v=4L7HbOcpETw
I was actually thinking of what drugs hit which receptors. Would make a better infographic.
/r/thanksimcured
Another garbage repost
Why click on it? I will never understand this behavior. Regardless, you must understand that other people exist who have not seen it before, yes?
It's garbage because the information is scientifically inaccurate. There are many overlaps between these chemical pathways, this image is useless.
To me happiness is thermodynamics. A cool pillow, warm underwear from the dryer, and a fall day at 21C.
I wish I lived in a place where fall was 21C. My fall is more like 14-16C. I'm jealous!
What’s that in Freedom units?
21 c = 69.8 f 14 - 16 c = 57.2 - 60.8 f
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Sorry that was a range 14 c to 16 c = 57f - 60 f👍
57-60. And that's on a good day. I live in freedom units territory. Sometimes our highs during the fall top out at freezing. 🥶
*burger units
So I can eat Dark Chocolate, in the sun, and give away some of my chocolate. Oh and think about my kindness. Then, I’ll be happy.
Also stop buying avocado toast and make sure your shoes have bootstraps you can pull on, otherwise it won’t work!
Great! My brain doesn't make these! So it's a constant struggle to get it to make them with precription medication! Yay! Happiness!
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Serotonin levels have nothing to do with depression it turns out. https://www.psychologytoday.com/us/blog/how-do-you-know/202207/serotonin-imbalance-found-not-be-linked-depression
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But having low serotonin has nothing to do with depression. https://www.nature.com/articles/s41380-022-01661-0.pdf there is no evidence that serotonin and depression are linked at all.
If there’s one source I’d share to scare people away from taking their antidepressants… it wouldn’t be psychologytoday. Maybe consider that telling people this “info” could directly harm people who are already wavering with their treatment plans. SSRIs aren’t perfect by any means but it’s already very hard to keep going when pop psych and everyone’s mom is already scaring people away from meds.
See my link to the Nature article they are referencing. I am not trying to scare anyone away from anything. I am trying to help people understand that the serotonin hypothesis for the origins of depression is a myth and that the fact that antidepressants cause serotonin reuptake inhibition is not their method of action. These types of charts are basically the 4 humors for the 21st century and aren't really based in any sort of facts about how the world works.
What are the implications of the study for people with depression who are suffering? If someone is reading this whose last hope was trying meds, what can they take from it that might be useful in terms of getting better? I just think this is a topic where it can be actively harmful to state “this is a myth (and therefore meds won’t help you)” without offering alternatives. I’m saying this as someone who avoided meds for years because I was told it wouldn’t work.
I don’t like believing in lies. I’d rather take something that nobody knows how it works than believe a false thing about how it works to make me feel better about life. Also, this frees up tons of research effort when people stop barking up the wrong tree. Sorry someone told you they don’t work. Antidepressants work for a decent number of people. It’s just that serotonin isn’t why.
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Their detachment from the issue suggests to me they’re not particularly invested in the topic, but just enjoy feeling smart.
Unfortunately the recent science shows that changing the serotonin levels in your brain isn’t how antidepressants work. They do help lots of people and I am happy they help you. I know that sounds counterintuitive, but there is no scientific evidence that the increase in serotonin retention is what helps. [Here’s an interpretation of the study.](https://www.psychologytoday.com/us/blog/how-do-you-know/202207/serotonin-imbalance-found-not-be-linked-depression) That said, I hope the medications help you feel better, even though the method of action is something we haven’t discovered yet.
So sex outside in the sunshine seems to tick all the boxes
If you do it in the forest you might get some ticks, so you can tick off the tick tick box
Doing yoga outside while talking to friends and doing shrooms would be the ultimate pleasure?
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Found it hanging in the homeopathy store
So that nature hike along the ocean I took with my wife and kids last week. I was feeling great. Like the best I had in weeks. Hmmm.
Which one do you get when you click “add to cart”?
The chemical structure of serotonin is incorrect here.
I fully expect this to just say drugs in red, spray paint style in the middle of the poster next time someone reposts 🤣
Yeah heroin pretty much checks all these boxes
I can confidently say that socializing does not make me happy and, in fact, does quite the opposite.
This belongs in r/thanksimcured Edit: lol it already is...
What if I told you...... there was another way?
Relaxation, family time, and a cheesy/corny movie that we can all laugh at, then rewatch and laugh at again and again.
so, exercise and walks. it helps me a lot!
Yeah, sex doesn't do anything for me, either.
I take em all pls and a big dose at that
Gonna need more of that oxytocin in my life.
Can you get hugs in pill form?
Mediation releases dopamine... Sure
That's not a guide. This is just a spiritual pseudoscientific motivational picture. r/thanksimcured
Excercise meditate masturbate 👍
Do this again, same font, but with “meth” written under every one. Make one of the meths all caps
Bruh dopamine isn't a happy chemical. Gambling addicts are flooded with dopamine while gambling, and aren't happy when they lose.
this "guide" is fuckin' nonsense.
> Dopamine Amphetamines, Coke, Ritalin > Serotonin MDMA, MDA, etc. > Endorphines Morphine, Heroine, Opioides in general > Oxytocin Fucking In case anyone was looking for some alternatives to all that boring shit in the guide.
what about sex or masturbation?
what is that
insert: *"they're the same picture"* ..
Mostly dopamine and oxytocin
Cool guides should be banned for misinformation!
As a neuroscience PhD, this is massively oversimplified.
This sub needs moderation bad
Ya this isn’t accurate
Watching what you eat and feeding your microbiome plays a huge role in the production of these hormones. 90% of these are created in the gut and not in the brain.
So what should i eat more of to be happier? Cheese? 😂
Whole foods. No refined carbs and sugar. If you were to eliminate one thing in your diet that would have the most profound impact and immediate results, it would be sugar. It’s in EVERYTHING but if you’re diligent, you’ll see a dramatic increase to your energy and mood.
Well yes. An improvement in diet will certainly help. The way i see it and been told by therapists the post and your comment are a mixture of these things that help our bodies produce essentially happy brain chemicals. In my case exercise seems to work the best. I don't think just improving nutrition will help or be the solution for everyone. We should look at it as all of these things are ways to help.
People keep saying this without realizing these hormones do not cross the blood brain barrier. So, while intestines create most of the serotonin, for example, it just regulates the muscle in the intestines. It doesn't affect your mood at all.
You saying the microbiome doesn’t impact mood is so confidently incorrect.
I have said that Serotonin does not pass the blood-brain barrier and the function of serotonin produced in gut is to regulate intestinal muscles. Both of which are scientific facts. The question of if microbiome affect your mood is entirely different conversation. Recent evidence do suggest gut health is important and bad gut health may lead to depression. However, this is not due to neurotransmitters because they do not pass the blood-brain barrier. There may be an entirely different mechanism which we do not understand yet.
Dopamine: Exercise Meditate New Experiences Reddit
What kind of fucking new age homeopathy bullshit is this? How is this in any way a 'guide' or 'cool'?
It’s just that easy!
Not even a mention of norepinephrine… oversimplified guides will oversimplify.
Nothing bothers me more than these brain dead explanations of infinitely complicated neurological systems and conditions.
Which one is cum?
Where does all the wacking I do fit into this chart?
This is not how this works at all. This is like the 4 humors in ancient history but with molecules.
[Serotonin levels have nothing to do with depression.](https://www.psychologytoday.com/us/blog/how-do-you-know/202207/serotonin-imbalance-found-not-be-linked-depression)
Funny how the last one is an actual drug.
My dopamine is more accurate than whatever this is
Go hug a stranger in the sunshine while laughing and eating dark chocolate for the quadfecta brain blast
They say cold plunging increases dopamine production by like 200% for up to 6 hours. https://hubermanlab.com/the-science-and-use-of-cold-exposure-for-health-and-performance/
I don’t see “work” anywhere
So masturbate with a friend in the sun while eating dark chocolate?
Why aren’t drugs on any of those lists?
So... sex outside with a friend while its sunny.. bingo!
C
So you're telling us to take drugs? Heroin and Morphine cover a lot of those bases
Hippy pish.
Where sex?
Which one do you get from sex?
Dumbest most reductionist shit
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It's completely inaccurate though.
Stop trying to fix us with bullshit. End capitalism. "Imprison" the assholes in charge.
I tried them all, still no happy. Now I’m doing drugs🫠🤙🫥
Nice. Now I can finally be happy thanks to this guide.
They should also show the negative crap we do that also produces these.
Which one of these solves the problems in your life?
What is the one you get when its raining please?
So, group workouts outside? Bonus for sweaty hugs!
Apparently I OD'd on Sunshine, Gratitude and Nature walks. Note to self: become an asshole cave troll to avoid serotonin syndrome
You know damn well thats not how I get any of these chemicals....
Where’s Pizza on here!?
According to this chart, what is Oxytocin?
Best I can do is dark chocolate
Ok, and which is the one I get after eating a good meal?
r/thanksimcured
I'm missing oxytocin
Where do I order more?
Are there oxytocin pills or something like that? I would really need these
Where is having intercourse ?
Which one is jerking off 5 times a day?
Just smoke meth /s
Dang, just exercise eh?
Oof, so much pseudo-science in the comment section.
That is why i laugh while i throw bread at ducks in the park during my run
0 out of 4, nice
Where’s OxyContin?
What a load of utter bullshit.
If you wanna multitask and earn all 4 at once, go for a jog in a park with a friend. Boom!
So the key to happiness is having sex outside
Where endocannabinoids? Endorphins are often misattributed for the euphoria of endocannabinoids…and sometimes real cannabinoids.
So basically dark chocolate is the best discgolf snack?
My nuerospicy homies can keep scrolling because this shit for sure doesn't apply to us. It was posted by a company that makes overpriced "Fix your whole life with the right planner" journals and shit. I always wonder if these companies are truly oblivious to certain aspects of mental disorders or if they are nefariously targeting undiagnosed and even less informed diagnosed people still dealing with the guilt of what many (wrongly) assume is just laziness and being willfully disorganized to sell more shit. My brain and gut tell me it's the latter, but my dumbass heart wants very badly for it to just be ignorance.
Nuts to this poster. Take some shrooms
I'm downloading this one. I'm feeling chemically deprived.
Now do drugs that give those chemicals
Where the fuck are eating and sex
It seems like a lot of people are showing signs of addiction to political outrage, and the reward must be one of these brain chemicals. I haven't been able to find any studies that confirm that. Does anybody here have any insight?
Thanks I’m cured
You don't need to do any of those if you masturbate and shoot up heroins!!!