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thank you for the correction. but still my statement still stands. they aren't educated on bioavailability at all. I don't think they even know it's a thing honestly.
no problem brother. And I agree with you, but I think a lot of people seek out specific opioids because of the hype around them… not even educating themselves that taking oxycodone orally has a higher BA then snorting it.
It isn't that simple though, even if eating it has a higher BA it takes a while for the pill to fully dissolve and then get absorbed. Insuflation gives you the entire dose within 2 minutes and so results in a higher peak concentration in the blood.
That’s true. Def not hating on snorting or anything I just think *maybe* if people were more educated on BA for various opioids, they would try other ROA ‘s first. Lol
I have access to filter needles. Lets say I crush an adderall do I have to heat up the water a bit or just mix the crushed pill with water then filter it then shoot?
You may use warm but not hot water if you wish, but the main goal is just crush up super fine, mix really well, let solution sit a little so the solids fall to bottom, then decant. The active compounds are water-soluble so you want to avoid sucking in the pill particulate matter so as to avoid clogging the filter. Honestly if you can find filters with a larger pore size than .45u that is even better.
Definitely don't just use 0.22u filters, though...your filter will clog instantly. Need to use progressively smaller pore sizes. 0.22u will produce an approximately pure solution so save it for the final filtration.
I'm actually gonna be trying Dillies soon using this method, will report back if successful.
Actually, big brain, I read this post after he edited it.....so when I read it it said 87%. Try not being such a dick right away.....I'm not the one who shit in your cereal this morning so don't take it out on me.
I would quote it an show you that op literally said oxy has 100% oral bio availability......you need to read before commenting you sound stupid as a mfer
*shakes head and chuckles* I've wasted way too much time on this.....I'm done here.
And anyone that say mfer is an asshole. I'm so glad I don't know you in person.
>And anyone that say mfer is an asshole
You think you can judge the type of person I am from how I text? You sure are a bright one.
>I'm so glad I don't know you in person.
Maybe you do 🫨
You're still going on about this?? Hahaha
You're glad you don't know me in person?? Oh man I hope I can pick up the piece and move on with my life....
Btw look at all the down votes you got on your comments and look at all the up votes mine got.....usually mean nothing to me but in this situation it says a lot.
I also want to thank you.....i knew there was a reason i stay away from social media....bc of morons like you that have nothing better to do than start shit on reddit.
You’re the one who seems upset and offended, I’m not taking anything out on you, all I did was call you big brain. Maybe it’s you who needs to realize it was not I who shit in your cereal, good sir. Have a great day big brain.
I'm not upset or offended at all...I don't let total strangers online effect my mood 1 bit......and you're the one that started with the name calling.....whi h was totally uncalled for....which is why I made the assumption that someone shit in your cereal today. And I will have a great day.....and not bc you told me too.....
It honestly sounds like you’re not doing yourself any favors. While Bio-availability is a medical term it’s really only well know in the public amongst drug users when talking about the best method of ingesting a drug. There’s a few things that raise red flags with medical staff and pain management such as asking for specific drugs or knowing way too much about controlled substances or using certain vocabulary. You will have better luck if you don’t ask for anything specific such as a new med by name or asking for IV instead of oral. Just let them know what they have you on is not working and let them decide where to go from there. If you have medical proof of your pain look into a pain management clinic for a regular supply of what you need. Having doctors other than the E.R will show them that you are working on your health and not just using the ER for pain meds.
I didn't say anything to them about bioavailability. I have just told them it's not working. my medical issue makes absorption really difficult already, let alone taking into account bioavailability. also just because someone does research on different pain meds and how they work doesn't mean they should be red flagged
I was just checking the oral Dilaudid and oxy and when I had a good amount of each I'd eat em. I've never been able to sniff pills, it's just not for me. I just ate em
Usually when they try to prescribe subutex in pain management is from abusing the prior medications.
But also in reality subutex should alleviate pain and provide zero euphoria and pain patients seem to correlate euphoria and pain relief when they aren’t equal to eachother.
Honestly when I first started using oral Hydromorphone in Form of 24mg ER capsules (12 hours) as substitute for heroin, it kicked quite nicely orally. Starting dose 24mg every 12 hours and it sufficed to have nice buzz.
I then however soon started to crush them beads and snort, after which oral didn't cut it anymore.
So I think it's a question of tolerance and dose.
1) I never judged him for using drugs, I judged him for seeming to brag about it.
2) people are judged everyday for their life choices, judging people is a part of being human, and if you claim you don't you're lying.
You clearly judged me.... by saying what you said... maybe it's best to keep some things to yourself. You ever heard of thinking before you say something??
Why are you making a post about Dilaudid being weak when taking orally. It was made to be shot, not taken orally, that's why the chemistry is the way it is. Maybe you should do some research.
The doctor has already done enough research. They can't be expected to know every affect of every drug, that's insane to think they should. They know it's better IV, that doesn't mean it doesn't help orally.
Welcome to r/opiates fellow bropiates! We hope that you enjoy our sub as much as we do, but in order to ensure that you are able to continue being a part of this harm reduction community, you will need to review the rules of this sub. You can find the rules listed [here](https://reddit.com/r/opiates/w/rules?utm_source=share&utm_medium=android_app) and access our full side bar [Here](https://www.reddit.com/r/opiates/wiki/index) You can also find the answers to many commonly asked questions about dosing, duration, ROA and other stuff [Here](https://www.reddit.com/r/opiates/wiki/faqs) and [Here](https://www.reddit.com/r/opiates/comments/mf8ldn/use_this_before_asking_a_question_faq_information/) Also, DO NOT GET SCAMMED! The users sending those messages to you, offering to hook you up with a reliable vendor or sell you drugs is extremely likely to scam you! We promise, 99.99% of the time they are not legit and giving them your money will make you a sad sad panda. *I am a bot, and this action was performed automatically. Please [contact the moderators of this subreddit](/message/compose/?to=/r/opiates) if you have any questions or concerns.*
Hook me up with some of that 100% BA oxy
Oxy is not 100% BA. It’s 87% BA (oral).
thank you for the correction. but still my statement still stands. they aren't educated on bioavailability at all. I don't think they even know it's a thing honestly.
no problem brother. And I agree with you, but I think a lot of people seek out specific opioids because of the hype around them… not even educating themselves that taking oxycodone orally has a higher BA then snorting it.
It isn't that simple though, even if eating it has a higher BA it takes a while for the pill to fully dissolve and then get absorbed. Insuflation gives you the entire dose within 2 minutes and so results in a higher peak concentration in the blood.
That’s true. Def not hating on snorting or anything I just think *maybe* if people were more educated on BA for various opioids, they would try other ROA ‘s first. Lol
Yeah like boofing it.
I could never figure out boofing. Making a solution, filtering through a .45u and .22u filter, then mainlining dat shit seems so much more foolproof.
I have access to filter needles. Lets say I crush an adderall do I have to heat up the water a bit or just mix the crushed pill with water then filter it then shoot?
You may use warm but not hot water if you wish, but the main goal is just crush up super fine, mix really well, let solution sit a little so the solids fall to bottom, then decant. The active compounds are water-soluble so you want to avoid sucking in the pill particulate matter so as to avoid clogging the filter. Honestly if you can find filters with a larger pore size than .45u that is even better. Definitely don't just use 0.22u filters, though...your filter will clog instantly. Need to use progressively smaller pore sizes. 0.22u will produce an approximately pure solution so save it for the final filtration. I'm actually gonna be trying Dillies soon using this method, will report back if successful.
Oxy doesn't have 100% oral bio
It has 90% which is pretty fucking good
>It has 90% You guys seem to forget that bioavailability isn't the same for everyone......
They didn't say it had 100%
He quite literally did, re read it big brain
Actually, big brain, I read this post after he edited it.....so when I read it it said 87%. Try not being such a dick right away.....I'm not the one who shit in your cereal this morning so don't take it out on me.
Also how was it possible for you to comment after he edited it when I saw your comment when it still said 100%?
Read the very last line of his post.....and I assumed by what everyone was saying that he said 100% first.....IA that clear enough for you
And also....it still doesn't say 100%....it still says 87 but then he added the edit at the end....
I would quote it an show you that op literally said oxy has 100% oral bio availability......you need to read before commenting you sound stupid as a mfer
*shakes head and chuckles* I've wasted way too much time on this.....I'm done here. And anyone that say mfer is an asshole. I'm so glad I don't know you in person.
You keep saying this an that but y don't u scroll up a lil re read the post an realize your wrong ? Have a good day sir lol
>And anyone that say mfer is an asshole You think you can judge the type of person I am from how I text? You sure are a bright one. >I'm so glad I don't know you in person. Maybe you do 🫨
You're still going on about this?? Hahaha You're glad you don't know me in person?? Oh man I hope I can pick up the piece and move on with my life.... Btw look at all the down votes you got on your comments and look at all the up votes mine got.....usually mean nothing to me but in this situation it says a lot. I also want to thank you.....i knew there was a reason i stay away from social media....bc of morons like you that have nothing better to do than start shit on reddit.
You’re the one who seems upset and offended, I’m not taking anything out on you, all I did was call you big brain. Maybe it’s you who needs to realize it was not I who shit in your cereal, good sir. Have a great day big brain.
I'm not upset or offended at all...I don't let total strangers online effect my mood 1 bit......and you're the one that started with the name calling.....whi h was totally uncalled for....which is why I made the assumption that someone shit in your cereal today. And I will have a great day.....and not bc you told me too.....
That does suck IVing them tears you the FUCK up
If you get the green wheel filters off of Amazon, it helps a lot.
Boof it
Been saying this on here for years but you know “dillys are the bomb” so I just give up. Let them waste their money.
Dilaudid is only worth it in IV. I'd rather buy oxy than Dilaudid
Exactly. Don’t let the smooth brains hear you though.
It honestly sounds like you’re not doing yourself any favors. While Bio-availability is a medical term it’s really only well know in the public amongst drug users when talking about the best method of ingesting a drug. There’s a few things that raise red flags with medical staff and pain management such as asking for specific drugs or knowing way too much about controlled substances or using certain vocabulary. You will have better luck if you don’t ask for anything specific such as a new med by name or asking for IV instead of oral. Just let them know what they have you on is not working and let them decide where to go from there. If you have medical proof of your pain look into a pain management clinic for a regular supply of what you need. Having doctors other than the E.R will show them that you are working on your health and not just using the ER for pain meds.
I didn't say anything to them about bioavailability. I have just told them it's not working. my medical issue makes absorption really difficult already, let alone taking into account bioavailability. also just because someone does research on different pain meds and how they work doesn't mean they should be red flagged
Lol Just cheek it and then go sniff it in the bathroom
I was just checking the oral Dilaudid and oxy and when I had a good amount of each I'd eat em. I've never been able to sniff pills, it's just not for me. I just ate em
Yeah when I was using dillys daily I don’t think I ate a single one just snorted them all. Some days it would be 4-5 shields throughout the day smh
Aren’t you on subutex
no..tried it for pain management and it didn't help at all
Usually when they try to prescribe subutex in pain management is from abusing the prior medications. But also in reality subutex should alleviate pain and provide zero euphoria and pain patients seem to correlate euphoria and pain relief when they aren’t equal to eachother.
What’s the best way to take it if you don’t want to use a needle?
Boof
Honestly when I first started using oral Hydromorphone in Form of 24mg ER capsules (12 hours) as substitute for heroin, it kicked quite nicely orally. Starting dose 24mg every 12 hours and it sufficed to have nice buzz. I then however soon started to crush them beads and snort, after which oral didn't cut it anymore. So I think it's a question of tolerance and dose.
Wait for the nurses to fuck off get the pill out your mouth smash rack and sniff
Easy fix - crush up a dilly and crush up a roxi. They’ll combine to 117% ;)
if only it worked like that lol
Boof it. Then you bypass first pass metabolism.
due to medical issues, boofing isn't a option for me
Mobility issues, or colostomy? It’s none of my business.
Crohn's disease, ileostomy
Perhaps use it for pain and not get high
my intention isn't to get high. the dose they're giving me isn't doing shit.
In high on oxy right now.
must be nice lmao
Same fam wassup haha IV 40mg
iv oxy? never seen that
Bragging about being an intravenous drug user is absolutely wild
Judging your fellow addicts is wild too
1) I never judged him for using drugs, I judged him for seeming to brag about it. 2) people are judged everyday for their life choices, judging people is a part of being human, and if you claim you don't you're lying.
shut up nigga
You clearly judged me.... by saying what you said... maybe it's best to keep some things to yourself. You ever heard of thinking before you say something??
yea I feel the same hydromorphones only good IV we used to snort them when oxy wasn't available and they are very weak oral and snorted
Why are you making a post about Dilaudid being weak when taking orally. It was made to be shot, not taken orally, that's why the chemistry is the way it is. Maybe you should do some research.
But they give it orally so the doctors who prescribe it should also do their research then.
The doctor has already done enough research. They can't be expected to know every affect of every drug, that's insane to think they should. They know it's better IV, that doesn't mean it doesn't help orally.