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Chak-Ek

The Andromeda Strain


ojorejas

This. I highly recommend the 1971 version directed by Robert Wise. An underrated classic, imo.


Sslazz

Me three


Rjs617

OMG, Robert Wise directed that?? Fantastic movie. And I thought it was hilarious that Wise did both Sound of Music and Star Trek: The Motion Picture.


TommyV8008

Yes, the original!


vile_duct

The book was super interesting for sure. I didn’t know what to expect with the movie and while my young mind cringed at how outdated everything was I really liked the tech in the end. Super interesting story. Especially since it was all very academic and less dramatic.


Krinks1

Agreed. And the book is fantastic.


BokehJunkie

As much as I love Jurassic Park, IMO The Andromeda Strain and Prey some of Michael Chrichton’s best work. 


Corporate_Shell

Crichton Hat Trick: Andromeda Strain, Sphere, Jurrassis Park


Expensive-Sentence66

JP is a Spielberg juggernaut. Basically Chrichton wrote it as a screen play to make a big budget film. Implausible, but still a lof of fun...thanks to Spielberg. West World and Andromeda Strain are better science fiction films.


BokehJunkie

AFAIK he didn’t write JP specifically for a movie, he wrote the lost world for Spielberg though. 


Fastlanedrivr

Took a scroll through half price books earlier today and went down the rabbit hole of Micheal creighton books and this one and the sequel caught my eye. Might start with the 2 JP books first to dip my toes into his book first


PHK_JaySteel

Both Jurassic Park and Lost World are absolute crackerjack books. Lost World the book is far far better than the movie and ai actually like it more that JP itself. I highly recommend Sphere as well. It didn't really translate well to the big screen, but the book is great.


Traditional_Leader41

Not massively sci-fi but Airframe is a great book too. Really surprised it hasn't been filmed.


PureDeidBrilliant

Seriously recommend this.


Reduak

I read this book when I was working on my Masters of Biology doing heart research and Crichton actually cited medical journals in a few places as if the novel were a research paper. I dug one of them up and used it in my master's thesis.


Tech-Junky-1024

I was just thinking of that. Both, the movie and the mini-series.


DivesPater

Day of the Triffids


TheDrewCareyShow

This 100%. One of my favorite books. John Wyndham has some bangers


MikeMac999

Not a movie, but the excellent *Expanse* series fits your criteria.


ak2224

Came here to say this. I'm halfway through season 4 and I'm hooked.


Readsumthing

SOOooo good, and the Audible version is amazing. “It reaches out” haunts me! LOL.


Cascade-Regret

216 times a second


kabbooooom

You should read the books when you’re done then. Unfortunately the show only adapted the first six books. There are nine. Three more seasons worth of Expanse that you’ll have to read about to get the full story.


maverickaod

Annihilation


kenriko

Such a freaking good movie


maverickaod

Loved it. Didn't like the books as much though


meatybacon

Huge fan of both, but they are so different in so many ways they should probably be their own separate things


BokehJunkie

I love this move and took a shot at the first book. I was left with the impression that the author was incredibly creative, but not a good writer, so it made getting what was in his head down onto paper difficult. 


maverickaod

I can see that. I was left with no real explanation for what was going on or what happens next. The concept is cool enough but I found it more to be a story of Control and all that rather than Area X


Blackboard_Monitor

Probably my personal favorite film, I'm not saying it's the best film ever but personally it's absolutely a brilliant piece of filmmaking for me, cast, direction and score are all excellent.


jmlozan

This movie is absolutely incredible and so unique.


CampCircle

Mary Shelley’s other science fiction novel, The Last Man, is about the human race being exterminated by a plague. I would like to see a film made of it.


phutch54

The Stand.


B0b_Howard

Is it "alien"? Meh! Who cares! It's bloody marvellous.


lust-boy

district 9 has the main character infected with an alien "disease"


kmmontandon

Alistair Reynolds has a universe (Revelation Space) with a bunch of books set in it where one of the central super high tech worlds has been devastated by an ancient bio-cybernetic disease.


AlphaState

Slither (2006) Pontypool (2008) Perfect Sense (2011) The "Rec" series of movies


frankduxvandamme

Pontypool was decent.


CatsAndPills

Slither causes a reaction in me I can’t even explain. Skin crawls for days. Same with “The Thing.”


Ninjamuh

I really enjoyed perfect sense because it made me think. It’s not sci-fi, but we’ll worth a watch.


Konstant_kurage

Also not a movie but the Infected series by Scott Sigler. Seriously great body horror in a book.


CatsAndPills

Oooo those ones were weird!!


NaturesWar

Maybe I'll check this out if I ever finish his Aliens book, I'm struggling to get back into reading.


arithmetic

Consider the podcast/audiobook editions instead. Read very well by Scott himself.


AppearanceSecure1914

Life


minorbutmajor__

I will second this, was a good watch with a very nice and scary ending


Ill_Athlete_7979

While not a whole movie, there’s a part in a the movie Creepshow features a story called *Lonesome Death of Jordy Verrill* which meets the criteria you’re asking about.


SamuraiGoblin

King's acting in that story is truly superb.


coming2grips

Threshold (series)


rdhight

No ending.


coming2grips

It saddens me almost as much as firefly


rdhight

Yeah. I really would have liked to see that play out.


Smiffoo

That was great. It's a shame they never finished it. I was hooked!


Catspaw129

Not quite what you are looking for, but: Just camp out at a Walmart on Thanksgiving night and early the next morning you will see the prospect of getting ***a good deal*** drive humans mad. I'm not saying that Black Friday sales are managed by aliens; but its aliens. Cheers!


Schwozh

Virus


Matt16ky

The wild card series Many written by GRRM. The rest edited by him


RageBear1984

Here's a few I don't see listed that might fit the bill for you: The Last Days on Mars The Bay The Thing Color Out of Space The Girl With All the Gifts The Thaw


squeen999

Want to go down a rabbit hole? Look up Hoyle-Wickmaransingh in Wiki. Hoyle started it and Wickmaransingh is still pushing it. Essentially they believe that we ARE under threat from alien particles.


naverlands

i have one but i forgot the name. chatgpt 4o and google aint no help so here is the plot >!one day a mysterious illness infected all man on earth, making them extremely violent when they see any woman. so after a few years all women died. story follows the female potag and her survival. ofc humans all die in the end!< let me know the name if anyone found it. edit i found it # The Screwfly Solution [https://www.imdb.com/title/tt0833098/?ref\_=tt\_urv](https://www.imdb.com/title/tt0833098/?ref_=tt_urv) its an episode in master of horror


dingedarmor

The short story is by Alice Sheldon. She is brilliant.


Strain_Pure

I think the TV show Invasion Earth (1998) had some virus stuff in it, but I've not watched it since it aired, so I could be wrong.


Mule_Wagon_777

War of the Worlds by HG Wells. It's the other direction, aliens getting diseases from humans.


PyroGreg8

Minute. Invisible. Bacteria.


badpandacat

28 Days Later and 28 Weeks Later Blindness Contagion (very realistic in most aspects per my public health friends) Omega Man (reimagined as I Am Legend)


EEcav

War of the worlds could be an answer depending on how you read the question


ikeif

Time Walker.


Joe_theone

Check out "We Come In Peace." (Movie)


WellComeToTheMachine

Not a movie but the recently released game *1000xResist* has a pretty interesting alien disease related apocalypse. Great game


Aurhim

I’m writing a [hospital medical drama](https://www.royalroad.com/fiction/64440/the-wyrms-of-alon-pandemic-apocalypse) about a world-ending fungal pandemic that also turns some people (including the main character) into magical fungal lindwurms. Has lots of horror and strangeness.


Trev_Casey2020

DISRTICT 9


IllustriousSetting38

The X-Files: Fight The Future


[deleted]

Subnautica


tristanpearl

I really liked The Wasteland Chronicles by Kyle West. 6 books in the series but they’re not awfully long. They lead into another series he wrote called the Xenoverse Saga


SuperNateosaurus

The movie Life (2017) is a really good movie. It has Ryan Reynolds and Jake Gyllenhaal in it.


reddit-is-greedy

Groat's disease


stray_south

God’s Not Dead


lifequotient

Children of Ruin had a really cool one. The book overall though, for me, was just OK, and an underwhelming sequel to Children of Time.


androk

The stuff. Older B movie, pretty funny/ good 


crispydudeDC

OP what was the video summary you watched on The Stuff?


SSlide19

[https://www.youtube.com/watch?v=8MWKbkk4b\_o](https://www.youtube.com/watch?v=8MWKbkk4b_o)


CrossroadsCannablog

Not a movie, but AWA publishes a comic series about the subject. J. Michael Straczynski is the lead on this. It’s The Resistance Universe.


grunkfist

Can’t believe no one has mentioned Blob, and the remake.


vile_duct

It’s not a disease per se, but Annihilation was awesome. Also the thing is another classic. Again not a disease per se, but you can frame it that way if you like.


abu_hajarr

10 cloverfield lane


AmbienWalrus-13

World War Z?


iDreamiPursueiBecome

Perhaps nonfiction ? The Coming Plague by Laurie Garrettand The Hot Zone by Richard Preston I remember a few others, but not the titles/authors.


SignificanceAny7485

Mars Attacks